Neurological Outcomes after Human Umbilical Cord Patch for In Utero Spina Bifida Repair in a Sheep Model
Abstract Objectives The objective of our study was to test the hypothesis that in utero repair of surgically created spina bifida in a sheep model using cryopreserved human umbilical cord Jumper (HUC) patch improves neurological outcome.Methods Spina bifida with myelotomy was surgically created in timed pregnant ewes at gestational day (GD) 75.The